Protocol MD

About · National DTC Peptide Therapy

Protocol MD. Physician-Designed Peptide Protocols.

Protocol MD brings physician-led, 503A-compounded peptide protocols to a national audience. We exist for anyone who wants to take their health seriously: build energy, lose weight, sleep better, recover from an injury, sharpen focus, or invest in long-term healthspan.

See Our Peptides
Protocol MD Sermorelin peptide vial

Our Mission

We Help Your Body Work With You — Not Against You.

Most options stop at the surface — a pill, a kit, a piece of vague advice. Protocol MD goes deeper. Peptides work with your body's own signaling — repair, energy, hormones, sleep, focus — and we track how you respond, so your physician can adjust your protocol to your goals.

  • 01

    Treatment at the Source

    Peptides work directly with the systems your body already runs — repair, energy, hormones, focus. No masking the symptoms.

  • 02

    Real Prescriptions

    Every protocol is prescribed by a US-licensed physician in your state. No questionnaire-and-ship.

  • 03

    503A Compounded

    All medications are made in US 503A compounding pharmacies — patient-specific, US-sourced, US-regulated.

Protocol MD NAD+ peptide vial

Physician-led, Experienced Clinicians

Real Medicine, Designed Around Your Goals.

Every protocol starts with a quick assessment — your goals, your health history, what you've already tried, and a safety check for anything that would rule peptides out. A US-licensed physician reviews your case and prescribes the right combination of peptides at the right dose for you.

From there, your care evolves with you. We follow up, watch how you respond, and adjust your dose if you need it. Not one-and-done. Not a kit. Not a guess.

Origin

Why We Built Protocol MD.

We started in a brick-and-mortar clinic in Scarsdale, New York. The people who came in looking for peptide therapy were the same kind of patient, over and over.

They'd been to their primary care doctor. The doctor didn't have peptide experience and couldn't prescribe. They'd looked online and found a hundred "research-grade" vials sold for $40 with a disclaimer that said "not for human use." They'd looked at telehealth — Hims, Ro, the rest — and none of them touched real peptide therapy. They'd looked at premium men's clinics and walked away because of the price, the travel, or the in-person commitment.

So they came to us. We treated them. They got better.

Protocol MD is what happens when you take that clinic and put it online. Physician-designed protocols, made in a US 503A pharmacy, prescribed by doctors who actually know peptide therapy, delivered to your door — without the markup of in-person concierge medicine or the risk of buying vials from a shipping container overseas.

We don't sell peptides. We design protocols. The compound is the ingredient. The protocol is the unit of value. That distinction is the entire reason this exists.

How It Works

From Quiz to First Shipment — Three Steps.

A licensed physician reviews every case. Medications ship cold to your door. Follow-ups happen on a regular cadence.

  1. 01

    Take the Assessment

    Answer a short health quiz — about 90 seconds. A US-licensed physician in your state reviews your case within 24 hours.

  2. 02

    Get Your Protocol

    Your physician prescribes the right combination of peptides for your goals and your body.

  3. 03

    Ship and Follow Up

    Shipped cold from a US pharmacy. Adjusted at follow-ups based on how you respond.

At Protocol MD,

We Believe Better Health Is a Protocol, Not a Product.

Find Your Protocol

Team

Meet the Team Behind the Protocols.

Board-certified physicians. Personalized care. Pharmaceutical-grade peptide therapy — delivered through secure, physician-guided telehealth.

Karl Ziermann, DO, Sports Medicine

Sports Medicine · DO

Karl Ziermann, DO

Medical Advisor

Education

  • BS in Exercise Science
  • MS in Clinical Nutrition
  • Doctor of Osteopathic Medicine — Lake Erie College of Osteopathic Medicine
  • Primary Care Sports Medicine Fellowship — University at Buffalo
  • Peptide Certification — SSRP

Dr. Ziermann's practice has been an evolution over time, applying information learned from earlier training to his current practice. He believes deeply in integrating nutrition and providing patient care that includes developing a nutritionally rich diet — a solid foundation to build upon. Another focus is the benefit of strength training, with patient care plans that incorporate a whole-body approach.

Dr. Ziermann's patient co-guided plan includes general medicine, a focus on metabolic systems, and hormone therapy. All of these components — alongside patient feedback — create a partnership and a pathway where people can achieve their greatest optimal health, wellness, and performance, both in their daily routines and beyond.

Russell Tigges, MD, Orthopedic Surgery

Orthopedic Surgery · MD

Russell Tigges, MD

Medical Advisor

Education

  • University of Iowa, BS BioMedical Engineering
  • Tufts University, Doctorate of Medicine
  • Board Certified in Orthopedic Surgery
  • Fellowship in Joint Reconstruction — Harvard & Tufts University
  • Fellowship in Functional Medicine — Kresser Institute
  • Certified in Peptide Management — SSRP
  • CrossFit Level 2 Instructor

Dr. Tigges has spent a lifetime caring for musculoskeletal health and now is focusing on longevity, healthspan optimization and functional health, where he crafts treatment strategies involving nutrition, exercise, hormonal balance and nutritional supplementation.

Embodying the principles he advocates, Dr. Tigges not only advises but also adheres to his health optimization methods, offering his people advanced and personalized care aimed at extending their healthspan and enhancing their life quality.

Richard Dentico, MD, Physical Medicine & Rehabilitation

Physical Medicine & Rehabilitation · MD

Richard Dentico, MD

Co-founder and Medical Advisor

Education

  • Binghamton University, BS Chemistry
  • New York Medical College, Doctorate of Medicine
  • UMDNJ-Rutgers / Kessler Institute Residency — Physical Medicine and Rehabilitation
  • UMDNJ-Atlantic Health System Fellowship — Pain Management and Sports Medicine
  • Diplomate of the American Board of Physical Medicine and Rehabilitation

Dr. Dentico's educational background and 15 years of clinical experience have culminated in exceptional expertise focused on optimizing physical health, enhancing performance, and enriching life experience. His comprehensive postgraduate education in functional medicine, anti-aging, and bioidentical hormone replacement therapy provides the foundation for his tailored treatment protocols, meticulously customized to meet each patient's unique needs.

Protocol MD provides a unique opportunity for people to benefit from Dr. Dentico's innovative approach to maximizing healthspan and physical performance.

What Every Protocol MD Patient Gets

Clinic-Quality Care, Delivered.

01

Physician-Prescribed

Every protocol designed and reviewed by a US-licensed physician within 24 hours.

02

US 503A Pharmacy

Compounded by Kaduceus and Greenwich RX — US-licensed 503A compounding pharmacies in Texas.

03

FedEx Overnight

Cold-shipped from a US pharmacy to your door within 2 business days of approval.

04

No Subscription

One charge per cycle. No autoship, no recurring billing, no membership lock-in.

How it works

From quiz to first shipment — three steps.

A licensed physician reviews every case. Medications ship cold to your door. Follow-ups happen on a regular cadence.

Step by step:

01

Take the assessment

Answer a short health quiz — about 90 seconds. A US-licensed physician in your state reviews your case within 24 hours.

02

Get your protocol

Your physician prescribes the right combination of peptides for your goals and your body.

03

Ship and follow up

Shipped cold from a US pharmacy. Adjusted at follow-ups based on how you respond.

At Protocol MD,

we believe better health is a protocol, not a product.

Find your protocol
503A US PharmacyPhysician-PrescribedThird-Party Tested

Built around you. Real medicine, designed by your physician.

Take the 60-second assessment