Protocol MD

Research & Guides

The peptide library, written by clinicians.

7 long-form articles on peptide therapy — what each compound does at the cellular level, who it’s for, what the FDA says about it, and where the gray-market vendors get the story wrong. Every guide is reviewed by a US-licensed physician and updated as evidence evolves.

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What Is Peptide Therapy? The Honest Explanation

Featured · Guides

What Is Peptide Therapy? The Honest Explanation

Peptide therapy uses short-chain amino acid signals your body already reads. Here's the real biology, the evidence limits, and how to tell a legitimate program from a vial with a wink.

Karl Ziermann, DO · 13 min read

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Is Peptide Therapy Safe? The Answer Depends on Who's Running the System

Guides · 11 min read

Is Peptide Therapy Safe? The Answer Depends on Who's Running the System

Is peptide therapy safe? The honest answer depends on physician screening, 503A sourcing, and structured monitoring. Here's what that looks like in practice.

Are Peptides Legal in 2026? The Actual Regulatory Framework

Guides · 14 min read

Are Peptides Legal in 2026? The Actual Regulatory Framework

Are peptides legal in the US? The answer is per-peptide and per-pathway. Here's how 503A compounding, the bulks list, the 2026 FDA reclassification, and gray-market law actually work.

Sermorelin: The GHRH Analog With a Stranger History Than You Think

Performance · 10 min read

Sermorelin: The GHRH Analog With a Stranger History Than You Think

Sermorelin was FDA-approved for 20 years, then quietly pulled — not for safety. Learn how this GHRH analog works, what the research shows, and when physician oversight matters.

NAD+ Injections: What the Mechanism Actually Tells You (And What It Doesn't)

Longevity · 14 min read

NAD+ Injections: What the Mechanism Actually Tells You (And What It Doesn't)

NAD+ injections deliver the coenzyme directly — bypassing the conversion steps that make oral precursors unreliable. Here's the mechanism, the honest evidence, and how to get started.

Glutathione Injection: What It Is, How It Works, and Why Route Matters

Longevity · 12 min read

Glutathione Injection: What It Is, How It Works, and Why Route Matters

Glutathione injection bypasses the GI tract to deliver the body's master antioxidant directly. Physician-prescribed, 503A compounded. Book a free consult.

503A Compounded Peptides: What the FDA's Review Actually Means

Guides · 14 min read

503A Compounded Peptides: What the FDA's Review Actually Means

503A compounded peptides are legal—but the rules are specific and changing fast. Here's what the April 2026 FDA reclassification, the July PCAC meeting, and the Category 1/2 framework actually mean for patients.

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